Prevalence of Candida in the oral cavity of diabetic subjects

J Assoc Physicians India. 2005 Jul:53:599-602.

Abstract

Objective: Estimation of prevalence of Candida in the oral cavity of diabetic and non-diabetic subjects.

Material and methods: One hundred and three subjects of diabetes mellitus (49 Type 1 diabetes mellitus and 54 Type 2 diabetes mellitus) and one hundred non-diabetic subjects (control) were studied.

Results: 41(83.67%) out of 49 Type 1 diabetes mellitus, 37(68.52%) out of 54 Type 2 diabetes mellitus and 27(27%) out of 100 in non-diabetic subjects were found to carry Candida in their oral cavity. Colony Forming Unit (CFU) of Candida in the oral cavity ranking in groups was Type 1 diabetes mellitus > Type 2 diabetes mellitus > non-diabetic subjects.

Conclusion: Colonization and carriage of Candida in the oral cavity was found to be higher in diabetic subjects than in non-diabetic subjects. However anti-diabetic therapy and glycaemic control in diabetes were found to bear no relation with carriage of Candida in the oral cavity.

MeSH terms

  • Candida / isolation & purification*
  • Candidiasis, Oral / epidemiology*
  • Candidiasis, Oral / etiology
  • Diabetes Complications / epidemiology*
  • Diabetes Complications / physiopathology
  • Diabetes Mellitus, Type 1 / complications*
  • Diabetes Mellitus, Type 2 / complications*
  • Female
  • Humans
  • India / epidemiology
  • Male
  • Mouth / microbiology*
  • Prevalence