Helicobacter pylori infection: prevalence in chronic urticaria patients and incidence of autoimmune urticaria (study in Dr. Cipto Mangunkusumo Hospital, Jakarta)

Acta Med Indones. 2007 Oct-Dec;39(4):157-62.

Abstract

Aim: To determine the prevalence of Hp infection in patients with chronic urticaria (CU) and to evaluate the result of autologous serum skin test (ASST) in CU patients with Hp infections.

Methods: In this cross-sectional study, 16 patients with chronic urticaria and 16 non-urticaria volunteers were investigated (matched for age and sex). All subjects were examined for Hp infection with the 13C-urea breath test. Autologous serum skin test was performed in patients with proven Hp infection.

Results: Helicobacter pylori was detected in 12.5% of patients and 0% of the control group. There was no significant difference between the two groups (p = 0.484 using Fisher exact test). Autologous serum skin test was positive in 1 of 2 CU patients with Hp infection.

Conclusion: In this study, there was no significant difference in the seroprevalence of Hp infection between CU patients and controls. Autologous serum skin test was positive in 1 of 2 CU patients with Hp infection.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Autoimmune Diseases / blood
  • Autoimmune Diseases / complications*
  • Autoimmune Diseases / immunology
  • Chronic Disease
  • Cross-Sectional Studies
  • Educational Status
  • Female
  • Helicobacter Infections / blood
  • Helicobacter Infections / diagnosis
  • Helicobacter Infections / epidemiology*
  • Helicobacter pylori / isolation & purification*
  • Humans
  • Incidence
  • Indonesia / epidemiology
  • Male
  • Middle Aged
  • Seroepidemiologic Studies
  • Urticaria / blood
  • Urticaria / complications*
  • Urticaria / immunology