INS-eGFP transgenic pigs: a novel reporter system for studying maturation, growth and vascularisation of neonatal islet-like cell clusters

Diabetologia. 2017 Jun;60(6):1152-1156. doi: 10.1007/s00125-017-4250-2. Epub 2017 Mar 18.
No abstract available

Keywords: Islet maturation; Pig; Reporter gene; Xenotransplantation.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Genetically Modified
  • Animals, Newborn
  • Gene Expression Regulation / genetics
  • Glucose / pharmacology
  • Green Fluorescent Proteins / genetics*
  • Humans
  • Insulin / genetics*
  • Insulin / metabolism
  • Insulin-Secreting Cells / metabolism
  • Islets of Langerhans / physiology*
  • Islets of Langerhans Transplantation
  • Male
  • Mice
  • Mice, Inbred NOD
  • Pancreas / cytology*
  • Pancreas / embryology
  • Pancreas / growth & development*
  • Sus scrofa
  • Swine

Substances

  • Insulin
  • Green Fluorescent Proteins
  • Glucose