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Development of a polymer stent with shape memory effect as a drug delivery system

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Abstract

The article presents a new concept for vascular endoprothesis (stent). Almost all commercially available stents are made of metallic materials. A common after effect of stent implantation is restenosis. Several studies on metal stents coated with drug show, that the use of a drug delivery system may reduce restenosis. The purpose of this work is to develop a new stent for the drug delivery application. The shape memory properties of thermoplastic polyurethane allow to design a new fully polymeric self-expandable stent. The possibility to use the stent as a drug delivery system is described.

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Authors and Affiliations

  1. Polymertechnik/Polymerphysik, Technische Universität Berlin, Fasanenstrasse 90, D-10623, Berlin, Germany

    H. M. Wache, D. J. Tartakowska, A. Hentrich & M. H. Wagner

Authors
  1. H. M. Wache
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  2. D. J. Tartakowska
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  3. A. Hentrich
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  4. M. H. Wagner
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Wache, H.M., Tartakowska, D.J., Hentrich, A. et al. Development of a polymer stent with shape memory effect as a drug delivery system. Journal of Materials Science: Materials in Medicine 14, 109–112 (2003). https://doi.org/10.1023/A:1022007510352

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  • DOI: https://doi.org/10.1023/A:1022007510352

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