Von Willebrand disease presenting as recurrent hemorrhage after transvaginal oocyte retrieval

Am J Obstet Gynecol. 2007 Apr;196(4):e10-1. doi: 10.1016/j.ajog.2007.01.025.

Abstract

A 34-year-old nulligravid woman experienced hemorrhage after each of 2 oocyte retrievals. Initial coagulopathy screening was negative. Treatments used during in vitro fertilization likely interfered with assay performance. Reevaluation remote from medications confirmed the diagnosis of von Willebrand disease. Treatments used during in vitro fertilization may increase bleeding risk and confound coagulopathy evaluation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Diagnosis, Differential
  • Female
  • Fertilization in Vitro / adverse effects*
  • Fertilization in Vitro / methods
  • Follow-Up Studies
  • Humans
  • Hysteroscopy / methods
  • Infertility, Female / complications*
  • Infertility, Female / diagnosis
  • Infertility, Female / therapy*
  • Ovulation Induction / adverse effects*
  • Ovulation Induction / methods
  • Recurrence
  • Risk Assessment
  • Severity of Illness Index
  • Uterine Hemorrhage / diagnosis
  • Uterine Hemorrhage / etiology*
  • Uterine Hemorrhage / therapy
  • von Willebrand Diseases / complications*
  • von Willebrand Diseases / diagnosis*
  • von Willebrand Diseases / therapy
  • von Willebrand Factor / analysis

Substances

  • von Willebrand Factor