The Washington PostDemocracy Dies in Darkness

For new cancer treatments, less is more

September 9, 2018 at 5:15 p.m. EDT
Tom Maguire of Pennsylvania was diagnosed with muscle-invasive bladder cancer this year and qualified for the bladder-preservation trial. (Michelle Gustafson/for The Washington Post)

Tom Maguire always figured that, if he ever developed cancer, he would pursue the toughest treatment available. “You destroy yourself, and then you can come back,” he said.

His view was tested earlier this year when he was diagnosed with bladder cancer that had invaded the muscle wall of the organ. The standard of care, he learned, usually involves removing the bladder. He would have the choice of permanently wearing a bag to collect his urine or having a difficult surgery to fashion a new bladder from his intestines. Both prospects filled the 63-year-old avid hiker and scuba diver with dread.