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Low-frequency rhythmic electrocutaneous hand stimulation during slow-wave night sleep: Physiological and therapeutic effects

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Abstract

Neocortical EEG slow wave activity (SWA) in the delta frequency band (0.5–4.0 Hz) is a hallmark of slow wave sleep (SWS) and its power is a function of prior wake duration and an indicator of a sleep need. SWS is considered the most important stage for realization of recovery functions of sleep. Possibility of impact on characteristics of a night sleep by rhythmic (0.8–1.2 Hz) subthreshold electocutaneous stimulation of a hand during SWS is shown: 1st night—adaptation, 2nd night—control, 3d and 4th nights—with stimulation during SWA stages of a SWS. Stimulation caused significant increase in average duration of SWS and EEG SWA power (in 11 of 16 subjects), and also well-being and mood improvement in subjects with lowered emotional tone. It is supposed that the received result is caused by functioning of a hypothetical mechanism directed on maintenance and deepening of SWS and counteracting activating, awakening influences of the afferent stimulation. The results can be of value both for understanding the physiological mechanisms of sleep homeostasis and for development of non-pharmacological therapy of sleep disorders.

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Authors and Affiliations

  1. J. S. Co. NEUROCOM, Moscow, Russia

    P. A. Indursky, V. V. Markelov & V. M. Shakhnarovich

  2. Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow, 117485, Russia

    V. B. Dorokhov

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  1. P. A. Indursky
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  2. V. V. Markelov
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  3. V. M. Shakhnarovich
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  4. V. B. Dorokhov
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Original Russian Text © P.A. Indursky, V.V. Markelov, V.M. Shakhnarovich, V.B. Dorokhov, 2013, published in Fiziologiya Cheloveka, 2013, Vol. 39, No. 6, pp. 91–105.

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Indursky, P.A., Markelov, V.V., Shakhnarovich, V.M. et al. Low-frequency rhythmic electrocutaneous hand stimulation during slow-wave night sleep: Physiological and therapeutic effects. Hum Physiol 39, 642–654 (2013). https://doi.org/10.1134/S0362119713060054

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  • DOI: https://doi.org/10.1134/S0362119713060054

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