Novel Management of Intractable Cervical Chylous Fistula with Local Application of Pseudomonas aeruginosa Injection

Otolaryngol Head Neck Surg. 2015 Oct;153(4):561-5. doi: 10.1177/0194599815584917. Epub 2015 May 22.

Abstract

Objective: Cervical chylous fistula is an uncommon complication after neck dissection, but it might lead to some serious clinical outcomes. Although most cervical chylous fistulas can heal in a few days with standard treatments, some can be intractable. In this study, we describe a new method with local application of Pseudomonas aeruginosa injection for intractable cervical chylous fistula.

Study design: Case series with chart review.

Setting: West China Hospital, Sichuan University, Chengdu, China.

Subjects and methods: The charts of 18 patients who were treated with P aeruginosa injection (PAI) for intractable cervical chylous fistula were retrospectively reviewed.

Results: All patients were successfully treated with PAI. Mild fever (temperature, <38°C) occurred in 9 patients, moderate fever (38°C-39°C) in 4 patients, and severe fever (>39°C) in 5 patients. All patients had mild to severe neck pain.

Conclusions: Local application of PAI is an effective method for the treatment of intractable cervical chylous fistula, of which the most common side effects are transient fever and local pain.

Keywords: Pseudomonas aeruginosa injection; chyle; fistula; neck dissection; thyroid carcinoma.

MeSH terms

  • Adult
  • Aged
  • Chyle*
  • Female
  • Fistula / therapy*
  • Humans
  • Injections
  • Male
  • Middle Aged
  • Neck
  • Pseudomonas aeruginosa*
  • Retrospective Studies