Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 2
1976 3
1977 1
1978 2
1979 2
1980 1
1981 4
1982 1
1983 7
1984 4
1985 3
1986 3
1987 2
1988 3
1989 3
1990 4
1991 1
1992 4
1993 3
1994 8
1995 1
1996 4
1997 1
1998 5
1999 1
2000 1
2001 3
2002 5
2003 2
2004 4
2005 3
2006 2
2007 4
2008 3
2010 1
2011 1
2012 4
2013 3
2014 1
2015 2
2018 1
2019 3
2020 1
2021 1
2022 1
2023 3
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

118 results

Results by year

Filters applied: . Clear all
Quoted phrase not found in phrase index: "steoroids"
Page 1
Evidence for DNA and protein binding by styrene and styrene oxide.
Phillips DH, Farmer PB. Phillips DH, et al. Crit Rev Toxicol. 1994;24 Suppl:S35-46. doi: 10.3109/10408449409020139. Crit Rev Toxicol. 1994. PMID: 7818770 Review.
Styrene is metabolized to styrene oxide, a direct-acting mutagen and carcinogen. Styrene oxide reacts with DNA mainly at the N-7 position in guanine, but also at other sites and with other bases. ...The available evidence indicates, therefore, that sty …
Styrene is metabolized to styrene oxide, a direct-acting mutagen and carcinogen. Styrene oxide reacts with DNA m …
Critical review of styrene genotoxicity focused on the mutagenicity/clastogenicity literature and using current organization of economic cooperation and development guidance.
Moore MM, Pottenger LH, House-Knight T. Moore MM, et al. Environ Mol Mutagen. 2019 Aug;60(7):624-663. doi: 10.1002/em.22278. Epub 2019 Mar 13. Environ Mol Mutagen. 2019. PMID: 30786062 Free PMC article. Review.
Styrene is an important high production volume chemical used to manufacture polymeric products. In 2018, International Agency for Research on Cancer classified styrene as probably carcinogenic to humans; National Toxicology Program lists styrene as reasonably anticipated t …
Styrene is an important high production volume chemical used to manufacture polymeric products. In 2018, International Agency for Research o …
Mutational signatures associated with exposure to carcinogenic microplastic compounds bisphenol A and styrene oxide.
Hu X, Biswas A, Sharma A, Sarkodie H, Tran I, Pal I, De S. Hu X, et al. NAR Cancer. 2021 Mar 1;3(1):zcab004. doi: 10.1093/narcan/zcab004. eCollection 2021 Mar. NAR Cancer. 2021. PMID: 33718875 Free PMC article.
Even within the same cancer type, proportions of corresponding mutational patterns vary among the cohorts from different countries, as does the amount of microplastic waste in ocean waters. BPA and SO are relatively mild mutagens, and other environmental agents can also po …
Even within the same cancer type, proportions of corresponding mutational patterns vary among the cohorts from different countries, a …
Styrene: toxicity studies--what do they show?
Roe FJ. Roe FJ. Crit Rev Toxicol. 1994;24 Suppl:S117-25. doi: 10.3109/10408449409020144. Crit Rev Toxicol. 1994. PMID: 7818769 Review.
Styrene is efficiently metabolized to styrene oxide, which is itself readily detoxified by the same enzymes as those involved in the metabolism of various foodstuffs. ...Exposing mice to doses of styrene high enough to overwhelm the capacity of the body to detoxify …
Styrene is efficiently metabolized to styrene oxide, which is itself readily detoxified by the same enzymes as those involved …
The response of Escherichia coli to the alkylating agents chloroacetaldehyde and styrene oxide.
Muenter MM, Aiken A, Akanji JO, Baig S, Bellou S, Carlson A, Conway C, Cowell CM, DeLateur NA, Hester A, Joshi C, Kramer C, Leifer BS, Nash E, Qi MH, Travers M, Wong KC, Hu M, Gou N, Giese RW, Gu AZ, Beuning PJ. Muenter MM, et al. Mutat Res Genet Toxicol Environ Mutagen. 2019 Apr;840:1-10. doi: 10.1016/j.mrgentox.2019.02.001. Epub 2019 Feb 7. Mutat Res Genet Toxicol Environ Mutagen. 2019. PMID: 30857727 Free PMC article.
DNA-damaging alkylating agents are present in environmental toxicants as well as in cancer chemotherapy drugs and are a constant threat, which can lead to mutations or cell death. ...In this work, we probed the cellular responses to the alkylating agents chloroacetaldehyde …
DNA-damaging alkylating agents are present in environmental toxicants as well as in cancer chemotherapy drugs and are a constant thre …
Review of the metabolic fate of styrene.
Sumner SJ, Fennell TR. Sumner SJ, et al. Crit Rev Toxicol. 1994;24 Suppl:S11-33. doi: 10.3109/10408449409020138. Crit Rev Toxicol. 1994. PMID: 7818768 Review.
Styrene and styrene oxide have been implicated as reproductive toxicants, neurotoxicants, or carcinogens in vivo or in vitro. ...Extensive investigations have been conducted on the kinetics of styrene and styrene oxide in rodents. In people, the …
Styrene and styrene oxide have been implicated as reproductive toxicants, neurotoxicants, or carcinogens in vivo or in …
Styrene respiratory tract toxicity and mouse lung tumors are mediated by CYP2F-generated metabolites.
Cruzan G, Carlson GP, Johnson KA, Andrews LS, Banton MI, Bevan C, Cushman JR. Cruzan G, et al. Regul Toxicol Pharmacol. 2002 Jun;35(3):308-19. doi: 10.1006/rtph.2002.1545. Regul Toxicol Pharmacol. 2002. PMID: 12202046 Review.
In rats, no effects on terminal bronchioles are seen, but effects in the nasal olfactory epithelium do occur, although to a lesser degree and from higher exposure concentrations. In addition, cytotoxicity and tumor formation are not related to blood levels of styrene or …
In rats, no effects on terminal bronchioles are seen, but effects in the nasal olfactory epithelium do occur, although to a lesser degree an …
DNA adducts in experimental cancer research.
Hemminki K, Försti A, Mustonen R, Savela K. Hemminki K, et al. J Cancer Res Clin Oncol. 1986;112(3):181-8. doi: 10.1007/BF00395910. J Cancer Res Clin Oncol. 1986. PMID: 3536940 Review.
The role of DNA adducts in the initiation of cancer is scrutinized in this presentation. Work on the activation of oncogenes, particularly on ras, has provided new evidence to link DNA adducts and tumour formation. Polycyclic hydrocarbons and nitroso compounds can cause ac …
The role of DNA adducts in the initiation of cancer is scrutinized in this presentation. Work on the activation of oncogenes, particu …
Effects of styrene on the reproductive health of women: a review.
Lindbohm ML. Lindbohm ML. IARC Sci Publ. 1993;(127):163-9. IARC Sci Publ. 1993. PMID: 8070863 Review.
Styrene has been shown to cross the placenta. Studies in animals suggest that styrene and styrene oxide have embryotoxic or fetotoxic effects early in pregnancy, but there is no evidence with regard to teratogenicity. ...Two studies also suggested association …
Styrene has been shown to cross the placenta. Studies in animals suggest that styrene and styrene oxide have embryotoxic or fe …
A re-evaluation of the cytogenetic effects of styrene.
Scott D, Preston RJ. Scott D, et al. Mutat Res. 1994 Dec;318(3):175-203. doi: 10.1016/0165-1110(94)90014-0. Mutat Res. 1994. PMID: 7527484 Review.
There is no convincing evidence of styrene clastogenicity in experimental animals. Styrene oxide is clastogenic only at lethal concentrations via i.p. injection in Chinese hamsters (but not via inhalation) or after oral treatment of mice, a route considered inapprop …
There is no convincing evidence of styrene clastogenicity in experimental animals. Styrene oxide is clastogenic only at lethal …
118 results