Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News Feature
  • Published:

Immunology: The pursuit of happiness

Researchers have struggled to identify how certain states of mind influence physical health. One biologist thinks he has an answer.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Kiecolt-Glaser, J. K. et al. Psychosom. Med. 46, 7–14 (1984).

    Article  CAS  Google Scholar 

  2. Kiecolt-Glaser, J. K., Speicher, C. E., Holliday, J. E. & Glaser, R. J. Behav. Med. 7, 1–12 (1984).

    Article  CAS  Google Scholar 

  3. Cohen. S., Janicki-Deverts, D. & Miller, G. E. J. Am. Med. Assoc. 298, 1685–1687 (2007).

    Article  CAS  Google Scholar 

  4. Cole, S. W. et al. Genome Biol. 8, R189 (2007).

    Article  Google Scholar 

  5. Cole, S. W., Hawkley, L. C., Arevalo, J. M. G. & Cacioppo, J. T. Proc. Natl Acad. Sci. USA 108, 3080–3085 (2011).

    Article  ADS  CAS  Google Scholar 

  6. Black, D. S. et al. Psychoneuroendocrinology 38, 348–355 (2012).

    Article  Google Scholar 

  7. Creswell, J. D. et al. Brain Behav. Immun. 26, 1095–1101 (2012).

    Article  CAS  Google Scholar 

  8. Antoni, M. H. et al. Biol. Psychiatry 71, 366–372 (2012).

    Article  CAS  Google Scholar 

  9. Fredrickson, B. L. et al. Proc. Natl Acad. Sci. USA 110, 13684–13689 (2013).

    Article  ADS  CAS  Google Scholar 

  10. Brown, N. J. L., Sokal, A. D. & Friedman, H. L. Am. Psychol. http://dx.doi.org/10.1037/a0032850 (2013).

  11. Losada, M. Math. Comput. Model. 30, 179–192 (1999).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Supplementary Information

Listen

Can our mental state affect our ability to fend off and fight disease? The Nature Podcast investigates.

Related links

Related links

Related links in Nature Research

Social neuroscience and health: neurophysiological mechanisms linking social ties with physical health 2012-Apr-15

A matter of the heart 2008-Mar-01

Stress and immunity 1999-May-27

Related external links

Steve Cole

The Atlantic: Meaning is healthier than happiness

Cousins Center for Psychoneuroimmunology

Stephen Smale

Positivity

Rights and permissions

Reprints and permissions

About this article

Cite this article

Marchant, J. Immunology: The pursuit of happiness. Nature 503, 458–460 (2013). https://doi.org/10.1038/503458a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/503458a

Search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research