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Quoted phrase not found in phrase index: "steoroids"
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Polychlorinated biphenyls (PCBs): mutagenicity and carcinogenicity.
Safe S. Safe S. Mutat Res. 1989 Jan;220(1):31-47. doi: 10.1016/0165-1110(89)90007-9. Mutat Res. 1989. PMID: 2492077 Review.
Based on the structure-activity relationships for PCBs (Safe, 1984) it is unlikely that the more toxic compounds such as 3,3',4,4',5-penta- and 3,3',4,4',5,5'-hexachlorobiphenyl, would form covalent adducts with DNA. (2) PCB mixtur …
Based on the structure-activity relationships for PCBs (Safe, 1984) it is unlikely that the more toxic compounds such as 3,3',4,4',5-penta- …
Adverse effects of neonatal exposure to 3,3',4,4',5,5'-hexachlorobiphenyl on hormone levels and testicular function in male Sprague-Dawley rats.
Xiao W, Zhang J, Liang J, Zhu H, Zhou Z, Wu Q. Xiao W, et al. Environ Toxicol. 2011 Nov;26(6):657-68. doi: 10.1002/tox.20677. Epub 2011 Mar 3. Environ Toxicol. 2011. PMID: 21374784
In this study, we investigated the time-course changes of hormone levels and sperm numbers in male Sprague-Dawley (SD) rats after neonatal exposure to 3,3',4,4',5,5'-hexachlorobiphenyl (PCB169). ...These results indic …
In this study, we investigated the time-course changes of hormone levels and sperm numbers in male Sprague-Dawley (SD) rats af …
Interference of polychlorinated biphenyls in hepatic and brain thyroid hormone metabolism in fetal and neonatal rats.
Morse DC, Groen D, Veerman M, van Amerongen CJ, Koëter HB, Smits van Prooije AE, Visser TJ, Koeman JH, Brouwer A. Morse DC, et al. Toxicol Appl Pharmacol. 1993 Sep;122(1):27-33. doi: 10.1006/taap.1993.1168. Toxicol Appl Pharmacol. 1993. PMID: 8378931
The effects of prenatal oral administration of 0.2, 0.6, and 1.8 mg/kg body wt of 3,3',4,4'5,5'-hexachlorobiphenyl (HCB) on Day 1 of gestation and a combination of 1 mg/kg 3,3',4,4'-tetrachlorobiphenyl (TCB) from Day 2 to Day 18 wi …
The effects of prenatal oral administration of 0.2, 0.6, and 1.8 mg/kg body wt of 3,3',4,4'5,5'- …
Effects of maternal exposure to 3,3',4,4',5-pentachlorobiphenyl (PCB126) or 3,3',4,4',5,5'-hexachlorobiphenyl (PCB169) on testicular steroidogenesis and spermatogenesis in male offspring rats.
Yamamoto M, Narita A, Kagohata M, Shirai M, Akahori F, Arishima K. Yamamoto M, et al. J Androl. 2005 Mar-Apr;26(2):205-14. doi: 10.1002/j.1939-4640.2005.tb01087.x. J Androl. 2005. PMID: 15713826 Free article.
On days 7-21 of gestation, Sprague-Dawley rats were orally administered 3 or 30 mug/kg/d of 3,3',4,4',5-pentachlorobiphenyl (PCB126) or 3,3',4,4',5,5'-hexachlorobiphenyl (PCB169) daily. Their male offspring were autopsied at 3, 6, …
On days 7-21 of gestation, Sprague-Dawley rats were orally administered 3 or 30 mug/kg/d of 3,3',4,4',5-pentachlorobiphenyl (PCB126) or 3 …
Inductive and inhibitory effects of non-ortho-substituted polychlorinated biphenyls on estrogen metabolism and human cytochromes P450 1A1 and 1B1.
Pang S, Cao JQ, Katz BH, Hayes CL, Sutter TR, Spink DC. Pang S, et al. Biochem Pharmacol. 1999 Jul 1;58(1):29-38. doi: 10.1016/s0006-2952(99)00070-2. Biochem Pharmacol. 1999. PMID: 10403516
The effects of a series of non-ortho-substituted polychlorinated biphenyls (PCBs) on human cytochrome P450 1A1 (CYP1A1), a 17beta-estradiol (E2) 2-hydroxylase, and P450 1B1 (CYP1B1), an E2 4-hydroxylase, were investigated in HepG2 and MCF-7 cells. ...Northern blot analyses …
The effects of a series of non-ortho-substituted polychlorinated biphenyls (PCBs) on human cytochrome P450 1A1 (CYP1A1), a 17beta-estradi …
2,2',4,4',5,5'- and 3,3',4,4',5,5'-hexachlorobiphenyl alteration of uterine progesterone and estrogen receptors coincides with embryotoxicity in mink (Mustela vision).
Patnode KA, Curtis LR. Patnode KA, et al. Toxicol Appl Pharmacol. 1994 Jul;127(1):9-18. doi: 10.1006/taap.1994.1133. Toxicol Appl Pharmacol. 1994. PMID: 8048058
Anestrous, juvenile female mink and pregnant adult mink were exposed to 3,3',4,4',5,5'-hexachlorobiphenyl (3HCB), a coplanar polychlorinated biphenyl (PCB), or 2,2',4,4',5,5'-hexachlorobiphenyl (2HCB), a noncoplanar PCB congener. B …
Anestrous, juvenile female mink and pregnant adult mink were exposed to 3,3',4,4',5,5'-hexachlo …
Milk transfer and neonatal uptake of coplanar polychlorinated biphenyl (PCB) congeners in mice.
Sinjari T, Klasson-Wehler E, Oskarsson A, Darnerud PO. Sinjari T, et al. Pharmacol Toxicol. 1996 Mar;78(3):181-6. doi: 10.1111/j.1600-0773.1996.tb00201.x. Pharmacol Toxicol. 1996. PMID: 8882352
The situation in the nursing neonate after maternal exposure to the same congeners is now studied: The 14C-labelled congeners 3,3',4,4'-tetrachlorobiphenyl (IUPAC number CB-77),3,3',4,4'5-pentachlorobiphenyl (IUPAC number CB-126), 3,3',4,4',5, …
The situation in the nursing neonate after maternal exposure to the same congeners is now studied: The 14C-labelled congeners 3,3',4,4'-tetr …
Potentiating effect of graphene nanomaterials on aromatic environmental pollutant-induced cytochrome P450 1A expression in the topminnow fish hepatoma cell line PLHC-1.
Lammel T, Boisseaux P, Navas JM. Lammel T, et al. Environ Toxicol. 2015 Sep;30(10):1192-204. doi: 10.1002/tox.21991. Epub 2014 Apr 5. Environ Toxicol. 2015. PMID: 24706484
For this purpose, cell cultures of the topminnow fish (Poeciliopsis lucida) hepatoma cell line PLHC-1 were simultaneously (and successively) exposed to graphene nanoplatelets (graphene oxide (GO) or carboxyl graphene (CXYG)) and an aryl hydrocarbon receptor (AhR) agonist (beta-na …
For this purpose, cell cultures of the topminnow fish (Poeciliopsis lucida) hepatoma cell line PLHC-1 were simultaneously (and successively) …
Induction of cytochrome P450 1B1 in MDA-MB-231 human breast cancer cells by non-ortho-substituted polychlorinated biphenyls.
Spink BC, Pang S, Pentecost BT, Spink DC. Spink BC, et al. Toxicol In Vitro. 2002 Dec;16(6):695-704. doi: 10.1016/s0887-2333(02)00091-7. Toxicol In Vitro. 2002. PMID: 12423652
The effects of 12 non-ortho-substituted polychlorinated biphenyl (PCB) congeners on the induction of human cytochrome P450 1B1 (CYP1B1), an estradiol 4-hydroxylase, were investigated in MDA-MB-231 breast cancer cells. ...Of the congeners investigated, 3,4,4',5-tetra …
The effects of 12 non-ortho-substituted polychlorinated biphenyl (PCB) congeners on the induction of human cytochrome P450 1B1 (CYP1B1), an …
Reactive oxygen species from the uncoupling of human cytochrome P450 1B1 may contribute to the carcinogenicity of dioxin-like polychlorinated biphenyls.
Green RM, Hodges NJ, Chipman JK, O'Donovan MR, Graham M. Green RM, et al. Mutagenesis. 2008 Nov;23(6):457-63. doi: 10.1093/mutage/gen035. Epub 2008 Jun 26. Mutagenesis. 2008. PMID: 18583386
Polychlorinated biphenyls (PCBs) are classified by the International Agency for Research on Cancer as probable human carcinogens. A subset of PCBs are described as 'dioxin like' because of similarities to 2,3,7,8-tetrachlorodibenzo-p-dioxin. ...In the current study, the ab …
Polychlorinated biphenyls (PCBs) are classified by the International Agency for Research on Cancer as probable human carcinogens. A s …
26 results