Falsely high glycated haemoglobin [HbA1C] because of haemoglobin OSU-Christiansborg

Clin Lab Haematol. 2005 Oct;27(5):334-5. doi: 10.1111/j.1365-2257.2005.00718.x.

Abstract

Glycated haemoglobin (HbA1c) is routinely used to assess the degree of glycaemic control in diabetic patients. We report a case of a 73 year old diabetic woman who had an elevated HbA1c of 13.4%. She was on maximum oral hypoglycaemic agents and was commenced on insulin. However, her HbA1c continued to remain high at 20.4%. Subsequent tests revealed that she had a haemoglobin variant, Haemoglobin Osu-Christiansborg, causing the falsely high glycated haemoglobin.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Diabetes Mellitus / diagnosis
  • False Positive Reactions*
  • Female
  • Glycated Hemoglobin / analysis*
  • Hemoglobinopathies / diagnosis*
  • Hemoglobins, Abnormal / analysis*
  • Humans
  • Hyperglycemia / diagnosis*
  • Hypoglycemic Agents / pharmacology
  • Insulin / pharmacology

Substances

  • Glycated Hemoglobin A
  • Hemoglobins, Abnormal
  • Hypoglycemic Agents
  • Insulin
  • hemoglobin Osu-Christiansborg