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Quoted phrase not found in phrase index: "steoroids"
Page 1
Maternal and Fetal Blood Pharmacokinetics and Organ Distribution of Atrazine, Propazine, Simazine, and Their Metabolites in Pregnant Rats After Chronic Oral Administration.
Brandhonneur N, Hutin V, Chevrier C, Cordier S, Le Corre P. Brandhonneur N, et al. Toxicol Sci. 2020 Feb 1;173(2):255-266. doi: 10.1093/toxsci/kfz223. Toxicol Sci. 2020. PMID: 31693143 Free article.
Exposure of rodents to atrazine (ATZ) has been associated with alterations of endocrine and reproductive functions by disrupting neuroendocrine control at hypothalamus level. Perinatal exposure to low doses of ATZ has been associated with reproductive dysfunc …
Exposure of rodents to atrazine (ATZ) has been associated with alterations of endocrine and reproductive functions by disrupti …
Pubertal development in female Wistar rats following exposure to propazine and atrazine biotransformation by-products, diamino-S-chlorotriazine and hydroxyatrazine.
Laws SC, Ferrell JM, Stoker TE, Cooper RL. Laws SC, et al. Toxicol Sci. 2003 Nov;76(1):190-200. doi: 10.1093/toxsci/kfg223. Epub 2003 Sep 11. Toxicol Sci. 2003. PMID: 12970575
We evaluated the effects of two ATR by-products, diamino-s-chlorotriazine (DACT) and hydroxyatrazine (OH-ATR), and a structurally similar chlorotriazine, propazine (PRO), on female pubertal development. Rats were gavaged from postnatal days (PNDs) 22 through PND 41 with DA …
We evaluated the effects of two ATR by-products, diamino-s-chlorotriazine (DACT) and hydroxyatrazine (OH-ATR), and a structurally similar ch …
In vitro metabolism of chlorotriazines: characterization of simazine, atrazine, and propazine metabolism using liver microsomes from rats treated with various cytochrome P450 inducers.
Hanioka N, Jinno H, Tanaka-Kagawa T, Nishimura T, Ando M. Hanioka N, et al. Toxicol Appl Pharmacol. 1999 May 1;156(3):195-205. doi: 10.1006/taap.1999.8648. Toxicol Appl Pharmacol. 1999. PMID: 10222312
The in vitro metabolism of chlorotriazines, simazine (SIZ), atrazine (ATZ), and propazine (PRZ) was studied using control, 3-methylcholanthrene-, phenobarbital-, pyridine-, dexamethasone-, and clofibrate-treated rat liver microsomes. ...The formation rates of SIZ-M1, ATZ-M …
The in vitro metabolism of chlorotriazines, simazine (SIZ), atrazine (ATZ), and propazine (PRZ) was studied using control, 3-methylch …
Triazine herbicides and their chlorometabolites alter steroidogenesis in BLTK1 murine Leydig cells.
Forgacs AL, D'Souza ML, Huhtaniemi IT, Rahman NA, Zacharewski TR. Forgacs AL, et al. Toxicol Sci. 2013 Jul;134(1):155-67. doi: 10.1093/toxsci/kft096. Epub 2013 Apr 16. Toxicol Sci. 2013. PMID: 23591565
The triazine herbicides, atrazine (ATR), simazine (SIM), propazine (PRO), terbuthylazine (TBA), and their chlorinated metabolites have been implicated in the etiology of testicular dysgenesis by altering steroidogenesis. To further investigate their effects on testoster
The triazine herbicides, atrazine (ATR), simazine (SIM), propazine (PRO), terbuthylazine (TBA), and their chlorinated metabolites hav …
Triazine herbicides inhibit relaxin signaling and disrupt nitric oxide homeostasis.
Park SE, Lim SR, Choi HK, Bae J. Park SE, et al. Toxicol Appl Pharmacol. 2016 Sep 15;307:10-18. doi: 10.1016/j.taap.2016.07.010. Epub 2016 Jul 16. Toxicol Appl Pharmacol. 2016. PMID: 27431321
Analyses of the simazine-exposed offspring revealed that the expression of the relaxin hormone receptor, relaxin-family peptide receptor 1 (RXFP1), prominently decreased in their ovaries and uteri. ...Therefore, the present study suggests that triazine herbicides act as …
Analyses of the simazine-exposed offspring revealed that the expression of the relaxin hormone receptor, relaxin-family peptide recep …
In vitro metabolism of simazine, atrazine and propazine by hepatic cytochrome P450 enzymes of rat, mouse and guinea pig, and oestrogenic activity of chlorotriazines and their main metabolites.
Hanioka N, Jinno H, Tanaka-Kagawa T, Nishimura T, Ando M. Hanioka N, et al. Xenobiotica. 1999 Dec;29(12):1213-26. doi: 10.1080/004982599237895. Xenobiotica. 1999. PMID: 10647908
The in vitro metabolism of chlorotriazines, simazine (SIZ), atrazine (ATZ) and propazine (PRZ) in liver microsomes from rat, mouse and guinea pig and the oestrogenic activity of chlorotriazines and their main metabolites have been studied. 2. ...
The in vitro metabolism of chlorotriazines, simazine (SIZ), atrazine (ATZ) and propazine (PRZ) in liver microsomes from rat, mouse an …
Effects of chloro-s-triazine herbicides and metabolites on aromatase activity in various human cell lines and on vitellogenin production in male carp hepatocytes.
Sanderson JT, Letcher RJ, Heneweer M, Giesy JP, van den Berg M. Sanderson JT, et al. Environ Health Perspect. 2001 Oct;109(10):1027-31. doi: 10.1289/ehp.011091027. Environ Health Perspect. 2001. PMID: 11675267 Free PMC article.
We determined effects on human aromatase (CYP19), the enzyme that converts androgens to estrogens, in H295R (adrenocortical carcinoma), JEG-3 (placental choriocarcinoma), and MCF-7 (breast cancer) cells; we determined effects on estrogen receptor-mediated ind …
We determined effects on human aromatase (CYP19), the enzyme that converts androgens to estrogens, in H295R (adrenocortical carcinoma …
Chronic toxicity of 1,3,5-triazine herbicides in the postembryonic development of the western clawed frog Silurana tropicalis.
Saka M, Tada N, Kamata Y. Saka M, et al. Ecotoxicol Environ Saf. 2018 Jan;147:373-381. doi: 10.1016/j.ecoenv.2017.08.063. Epub 2017 Sep 14. Ecotoxicol Environ Saf. 2018. PMID: 28869887
Seven 1,3,5- triazine (s-triazine) herbicides (ametryn, prometryn, dimethametryn, simazine, atrazine, propazine, and cyanazine) were tested using an amphibian (Silurana tropicalis) metamorphosis assay focusing on morphometric, gravimetric, and thyroid-histological e …
Seven 1,3,5- triazine (s-triazine) herbicides (ametryn, prometryn, dimethametryn, simazine, atrazine, propazine, and cyanazine) were …
Seasonal variation of chloro-s-triazines in the Hartbeespoort Dam catchment, South Africa.
Rimayi C, Odusanya D, Weiss JM, de Boer J, Chimuka L. Rimayi C, et al. Sci Total Environ. 2018 Feb 1;613-614:472-482. doi: 10.1016/j.scitotenv.2017.09.119. Epub 2017 Sep 26. Sci Total Environ. 2018. PMID: 28918279
Triazine herbicide concentrations in the Hartbeespoort Dam were in the order atrazine>simazine>propazine>ametryn>prometryn throughout the four seasons sampled. Triazine herbicide concentrations in the Hartbeespoort Dam surface water were highest in summer and g …
Triazine herbicide concentrations in the Hartbeespoort Dam were in the order atrazine>simazine>propazine>ametryn>prometry …
Chlorotriazine herbicides and metabolites activate an ACTH-dependent release of corticosterone in male Wistar rats.
Laws SC, Hotchkiss M, Ferrell J, Jayaraman S, Mills L, Modic W, Tinfo N, Fraites M, Stoker T, Cooper R. Laws SC, et al. Toxicol Sci. 2009 Nov;112(1):78-87. doi: 10.1093/toxsci/kfp190. Epub 2009 Aug 18. Toxicol Sci. 2009. PMID: 19690231
Previously, we reported that atrazine (ATR) alters steroidogenesis in male Wistar rats resulting in elevated serum corticosterone (CORT), progesterone, and estrogens. The increase in CORT indicated that this chlorotriazine herbicide may alter the hypothalamic-pituitary-adr …
Previously, we reported that atrazine (ATR) alters steroidogenesis in male Wistar rats resulting in elevated serum corticosterone (CORT), …
21 results