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1964 2
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1979 1
1980 2
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1989 4
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1999 3
2000 2
2001 9
2002 4
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Quoted phrase not found in phrase index: "steoroids"
Page 1
Extended Analysis and Evidence Integration of Chloroprene as a Human Carcinogen.
Sax SN, Gentry PR, Van Landingham C, Clewell HJ, Mundt KA. Sax SN, et al. Risk Anal. 2020 Feb;40(2):294-318. doi: 10.1111/risa.13397. Epub 2019 Sep 16. Risk Anal. 2020. PMID: 31524302 Free PMC article. Review.
beta-Chloroprene is used in the production of polychloroprene, a synthetic rubber. In 2010, Environmental Protection Agency (EPA) published the Integrated Risk Information System "Toxicological Review of Chloroprene," concluding that chloroprene was "likely t …
beta-Chloroprene is used in the production of polychloroprene, a synthetic rubber. In 2010, Environmental Protection Agency (EPA) pub …
Effects of the workplace on fertility and related reproductive outcomes.
Baranski B. Baranski B. Environ Health Perspect. 1993 Jul;101 Suppl 2(Suppl 2):81-90. doi: 10.1289/ehp.93101s281. Environ Health Perspect. 1993. PMID: 8243410 Free PMC article. Review.
The high prevalence of unsuccessful reproductive outcomes in the general population makes the design of human fertility studies difficult. ...The majority of reviewed papers on female fertility concerns the alterations of menstrual cycle and pregnancy …
The high prevalence of unsuccessful reproductive outcomes in the general population makes the design of human fertility studie …
Comparative carcinogenicity of 1,3-butadiene, isoprene, and chloroprene in rats and mice.
Melnick RL, Sills RC. Melnick RL, et al. Chem Biol Interact. 2001 Jun 1;135-136:27-42. doi: 10.1016/s0009-2797(01)00213-7. Chem Biol Interact. 2001. PMID: 11397379 Review.
Inhalation studies have demonstrated multiple organ tumorigenic effects with each of these chemicals in mice and rats. Sites of tumor induction by these epoxide-forming chemicals were compared to each other and to ethylene oxide, a chemical classified by the National Toxic …
Inhalation studies have demonstrated multiple organ tumorigenic effects with each of these chemicals in mice and rats. Sites of tumor …
Overview of the acute, subchronic, reproductive, developmental and genetic toxicology of beta-chloroprene.
Valentine R, Himmelstein MW. Valentine R, et al. Chem Biol Interact. 2001 Jun 1;135-136:81-100. doi: 10.1016/s0009-2797(01)00218-6. Chem Biol Interact. 2001. PMID: 11397383 Review.
beta-Chloroprene (CD), the 2-chloro derivative of 1,3-butadiene, is used for the manufacture of the synthetic rubber, polychloroprene. ...In a 90-day study with B6C3F1 mice, CD caused deaths at 200 p.p.m., the highest concentration tested, and epithelial hyperplasia of the …
beta-Chloroprene (CD), the 2-chloro derivative of 1,3-butadiene, is used for the manufacture of the synthetic rubber, polychloroprene …
Epidemiologic evidence for chloroprene carcinogenicity: review of study quality and its application to risk assessment.
Bukowski JA. Bukowski JA. Risk Anal. 2009 Sep;29(9):1203-16. doi: 10.1111/j.1539-6924.2009.01254.x. Epub 2009 Jun 24. Risk Anal. 2009. PMID: 19558388 Review.
This article evaluates the quality and weight of evidence associated with epidemiologic studies of cancer among occupational cohorts exposed to chloroprene. The focus is on liver, lung, and lymphohematopoietic cancers, which had been increased in early studies. ...O …
This article evaluates the quality and weight of evidence associated with epidemiologic studies of cancer among occupational cohorts …
1,3-Butadiene, isoprene and chloroprene: reviews by the IARC monographs programme, outstanding issues, and research priorities in epidemiology.
Rice JM, Boffetta P. Rice JM, et al. Chem Biol Interact. 2001 Jun 1;135-136:11-26. doi: 10.1016/s0009-2797(01)00175-2. Chem Biol Interact. 2001. PMID: 11397378 Review.
Studies of chloroprene exposed workers now include chemical workers from the United States, China and Armenia as well as shoe workers from Russia. The results of the studies from China, Armenia and Russia suggest an excess risk of liver cancer. The risk of other neo …
Studies of chloroprene exposed workers now include chemical workers from the United States, China and Armenia as well as shoe workers …
Toxicology of 1,3-butadiene, chloroprene, and isoprene.
Hurst HE. Hurst HE. Rev Environ Contam Toxicol. 2007;189:131-79. doi: 10.1007/978-0-387-35368-5_6. Rev Environ Contam Toxicol. 2007. PMID: 17193739 Review.
Additionally, studies document that these monomers can increase the tumor formation rate in various organs of rats and mice during chronic cancer bioassays. The extent of tumor formation versus animal exposure to these monomers varies significantly across spe …
Additionally, studies document that these monomers can increase the tumor formation rate in various organs of rats and mice during ch …
Using available in vitro metabolite identification and time course kinetics for beta-chloroprene and its metabolite, (1-chloroethenyl) oxirane, to include reactive oxidative metabolites and glutathione depletion in a PBPK model for beta-chloroprene.
Campbell JL Jr, Clewell HJ 3rd, Van Landingham C, Gentry PR, Andersen ME. Campbell JL Jr, et al. Front Pharmacol. 2023 Aug 17;14:1223808. doi: 10.3389/fphar.2023.1223808. eCollection 2023. Front Pharmacol. 2023. PMID: 37663267 Free PMC article.
Introduction: ss-chloroprene (2-chloro-1,3-butadiene; CP) causes lung tumors after inhalation exposures in rats and mice. ...Results: Model simulation of concentration dependence of disproportionate increases in reactive metabolite concentrations as exposures increases and …
Introduction: ss-chloroprene (2-chloro-1,3-butadiene; CP) causes lung tumors after inhalation exposures in rats and mice. ...Results: …
Occupational exposures associated with male reproductive dysfunction.
Schrag SD, Dixon RL. Schrag SD, et al. Annu Rev Pharmacol Toxicol. 1985;25:567-92. doi: 10.1146/annurev.pa.25.040185.003031. Annu Rev Pharmacol Toxicol. 1985. PMID: 2408559 Review.
This review focuses of industrial chemicals that research has indicated may adversely affect human male reproductive capacity. The study of male reproductive toxicity is impeded by a dearth of clinical endpoints. Males lack an obvious and easily measurable reprod …
This review focuses of industrial chemicals that research has indicated may adversely affect human male reproductive capacity. The st …
Identification of mammary carcinogens in rodent bioassays.
Bennett LM, Davis BJ. Bennett LM, et al. Environ Mol Mutagen. 2002;39(2-3):150-7. doi: 10.1002/em.10068. Environ Mol Mutagen. 2002. PMID: 11921183 Review.
The 9th Report on Carcinogens, issued in 2000, lists 21 of the 42 chemicals as human carcinogens including benzene, ethylene oxide, 1,3-butadiene, isoprene, chloroprene, C.I. basic red 9, and C.I. acid red 114. Ethylene oxide was associated with increased breast cancer …
The 9th Report on Carcinogens, issued in 2000, lists 21 of the 42 chemicals as human carcinogens including benzene, ethylene oxide, 1,3-buta …
79 results