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Association between KLK15 SNPs and prostate cancer risk in the QLD and PLCO study groups.

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posted on 2011-11-23, 02:43 authored by Jyotsna Batra, Felicity Lose, Tracy O'Mara, Louise Marquart, Carson Stephens, Kimberly Alexander, Srilakshmi Srinivasan, Rosalind A. Eeles, Douglas F. Easton, Ali Amin Al Olama, Zsofia Kote-Jarai, Michelle Guy, Kenneth Muir, Artitaya Lophatananon, Aneela A. Rahman, David E. Neal, Freddie C. Hamdy, Jenny L. Donovan, Suzanne Chambers, Robert A. Gardiner, Joanne Aitken, John Yaxley, Mary-Anne Kedda, Judith A. Clements, Amanda B. Spurdle
a

SNP identifier based on NCBI dbSNP; SNPs are included in the region of the KLK15 gene including 2 kb of transcription start sites.

b

The result of 2-d.f. test based on logistic regression in the Queensland study adjusted for age as continuous variable.

c

Imputed from 1000 Genomes project data and PLCO genotyped data, where actual genotype data not available, [27]; allelic OR and p values are presented.

d

The result of 2-d.f. test based on logistic regression in the PLCO study adjusted for age in five-year intervals, study center, and three eigenvectors to control population stratification in an incident density sampling strategy.

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