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2001 1
2002 1
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16 results

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Quoted phrase not found in phrase index: "steoroids"
Page 1
Potency of Hexaconazole to Disrupt Endocrine Function with Sex Hormone-Binding Globulin.
Alquraini A. Alquraini A. Int J Mol Sci. 2023 Feb 15;24(4):3882. doi: 10.3390/ijms24043882. Int J Mol Sci. 2023. PMID: 36835294 Free PMC article.
However, the endocrine-disrupting potential of hexaconazole is still under investigation. ...The potency of hexaconazole to bind with sex hormone-binding globulin (SHBG), a plasma carrier protein that binds androgens and oestrogens, is unknown. ...
However, the endocrine-disrupting potential of hexaconazole is still under investigation. ...The potency of hexaconazole …
Hexaconazole exposure disrupt acetylcholinesterase, leading to mental illness.
Ali A, Abdi SAH, Ali A, Ahmad W. Ali A, et al. Toxicol Res (Camb). 2023 Aug 18;12(5):775-782. doi: 10.1093/toxres/tfad067. eCollection 2023 Oct. Toxicol Res (Camb). 2023. PMID: 37915471
Hexaconazole is widely used in agricultural work, and it has been observed that it has potential to disrupt endocrine function and it has also capacity of bioaccumulation. ...Our findings revealed that hexaconazole has potency to interact with acetylcholinest …
Hexaconazole is widely used in agricultural work, and it has been observed that it has potential to disrupt endocrine function …
Enantioselective toxicity effect and mechanism of hexaconazole enantiomers to human breast cancer cells.
Yang N, Pang J, Huang Z, Zhang Q, Wang Z, Sun D. Yang N, et al. Food Chem Toxicol. 2023 Mar;173:113612. doi: 10.1016/j.fct.2023.113612. Epub 2023 Jan 18. Food Chem Toxicol. 2023. PMID: 36681264
This study aims to investigate the toxicity effect and mechanism of hexaconazole (HEX) to human breast cancer cell (MCF-7) at enantiomer levels. ...We further investigated the mechanism of enantioselective differences by using molecular docking which showed that CYP …
This study aims to investigate the toxicity effect and mechanism of hexaconazole (HEX) to human breast cancer cell (MCF-7) at …
Thyroid endocrine disruption in zebrafish larvae following exposure to hexaconazole and tebuconazole.
Yu L, Chen M, Liu Y, Gui W, Zhu G. Yu L, et al. Aquat Toxicol. 2013 Aug 15;138-139:35-42. doi: 10.1016/j.aquatox.2013.04.001. Epub 2013 Apr 18. Aquat Toxicol. 2013. PMID: 23685399 Free article.
The results showed that thyroxine (T4) levels were significantly decreased, while triiodothyronine (T3) concentrations were significantly increased after exposure to HEX and TEB, indicating thyroid endocrine disruption. Exposure to HEX significantly induced the tran …
The results showed that thyroxine (T4) levels were significantly decreased, while triiodothyronine (T3) concentrations were significantly in …
Hexaconazole exposure ravages biosynthesis pathway of steroid hormones: revealed by molecular dynamics and interaction.
Abdi SAH, Alzahrani A, Alghamdi S, Alquraini A, Alghamdi A. Abdi SAH, et al. Toxicol Res (Camb). 2021 Dec 16;11(1):60-76. doi: 10.1093/toxres/tfab113. eCollection 2022 Feb. Toxicol Res (Camb). 2021. PMID: 35237412 Free PMC article.
Widespread application of hexaconazole for agriculture purpose poses a threat to human health by disrupting normal endocrine homeostasis. ...If incessant exposure of hexaconazole occurs during agricultural work it may lead to ravage hormonal synthesis or pote …
Widespread application of hexaconazole for agriculture purpose poses a threat to human health by disrupting normal endocrine h …
The effects of hexaconazole and epoxiconazole enantiomers on metabolic profile following exposure to zebrafish (Danio rerio) as well as the histopathological changes.
Jia M, Wang Y, Wang D, Teng M, Yan J, Yan S, Meng Z, Li R, Zhou Z, Zhu W. Jia M, et al. Chemosphere. 2019 Jul;226:520-533. doi: 10.1016/j.chemosphere.2019.03.140. Epub 2019 Mar 26. Chemosphere. 2019. PMID: 30953897
In this study, zebrafish were separately exposed to 100 and 1000 mugL(-1) hexaconazole and epoxiconazole enantiomers for 21 d (1)H NMR-based metabolomics analysis showed that the exposure of low and high dose of hexaconazole enantiomers altered energy metabolism, li …
In this study, zebrafish were separately exposed to 100 and 1000 mugL(-1) hexaconazole and epoxiconazole enantiomers for 21 d (1)H NM …
Studies on the interaction of five triazole fungicides with human renal transporters in cells.
Nie J, Zhou J, Shen Y, Lin R, Hu H, Zeng K, Bi H, Huang M, Yu L, Zeng S, Miao J. Nie J, et al. Toxicol In Vitro. 2023 Apr;88:105555. doi: 10.1016/j.tiv.2023.105555. Epub 2023 Jan 18. Toxicol In Vitro. 2023. PMID: 36669674
Tebuconazole and penconazole inhibited OCTN2 (100 muM), while tebuconazole, triticonazole, hexaconazole, penconazole, and uniconazole inhibited MATE1 (100 muM). Tebuconazole and hexaconazole inhibited MATE2-K (100 muM). All five triazole fungicides were not substrat …
Tebuconazole and penconazole inhibited OCTN2 (100 muM), while tebuconazole, triticonazole, hexaconazole, penconazole, and uniconazole …
Conazole fungicides inhibit Leydig cell testosterone secretion and androgen receptor activation in vitro.
Roelofs MJE, Temming AR, Piersma AH, van den Berg M, van Duursen MBM. Roelofs MJE, et al. Toxicol Rep. 2014 May 22;1:271-283. doi: 10.1016/j.toxrep.2014.05.006. eCollection 2014. Toxicol Rep. 2014. PMID: 28962244 Free PMC article.
Conazole fungicides are widely used in agriculture despite their suspected endocrine disrupting properties. In this study, the potential (anti-)androgenic effects of ten conazoles were assessed and mutually compared with existing data. Effects of cyproconazole (CYPR …
Conazole fungicides are widely used in agriculture despite their suspected endocrine disrupting properties. In this study, the potent …
Effects of triazole fungicides on androgenic disruption and CYP3A4 enzyme activity.
Lv X, Pan L, Wang J, Lu L, Yan W, Zhu Y, Xu Y, Guo M, Zhuang S. Lv X, et al. Environ Pollut. 2017 Mar;222:504-512. doi: 10.1016/j.envpol.2016.11.051. Epub 2016 Dec 21. Environ Pollut. 2017. PMID: 28012672
We herein evaluated five commonly used triazole fungicides including bitertanol, hexaconazole, penconazole, tebuconazole and uniconazole for the androgenic and anti-androgenic activity using two-hybrid recombinant human androgen receptor (AR) yeast bio …
We herein evaluated five commonly used triazole fungicides including bitertanol, hexaconazole, penconazole, tebuconazole and uniconaz …
Influence of hexaconazole, carbofuran and ethion on soil microflora and dehydrogenase activities in soil and intact cell.
Kalam A, Mukherjee AK. Kalam A, et al. Indian J Exp Biol. 2001 Jan;39(1):90-4. Indian J Exp Biol. 2001. PMID: 11349536
From the result, it might be concluded that among the above three pesticides tested hexaconazole strongly inhibited the dehydrogenase system in bacteria including nitrogen fixing bacteria of soil and thus may affect soil fertility. It was concluded that hexaconaz …
From the result, it might be concluded that among the above three pesticides tested hexaconazole strongly inhibited the dehydrogenase …
16 results